Kusajili – Centralise les essais cliniques mondiaux

Kvælstofforiltes smertestillende effekt ved tandbehandling af børn Måle smerte på tand, muskel og hud ved inhalation af Niontix

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An investigation of the feasibility of using a topical formulation of lidocaine (SHACT) for hysteroscopy in women To obtain initial information regarding the feasibility of using SHACT as a formulation for hysteroscopy

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Determination of anti-inflammatory efficacy of topical formulations in a UV erythema test The objective of the study is the comparison of the efficacy of a generic corticosteroid formulation with the reference listed drug Psorcon® E Emollient Ointment and the comparators Volon® A Salbe ointment and Dermoxin® Salbe ointment on suppression of UV-induced erythema in subjects with healthy skin.

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A double-blind, randomised, controlled, multi-centre safety study of a refrigerator-stable formulation of VARIVAX® in healthy 12 to 15 month-old infants

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Randomizovaná, multicentrická, dvojitě slepá ověřovací studie k posouzení účinku opakovaných infúzí přípravku AIN457 (10mg/kg) oproti placebu na aktivitu onemocnění měřenou MRI scany po dobu 24. týdnů u pacientů s recidivující-remitující roztroušenou sklerózou To determine the effect of AIN457 (10 mg/kg i.v.) administered week 0, 2, 4, 8, 12, 16 and 20 compared to placebo on the number of combined unique active lesions (CUAL) observed on brain MRI scans performed every 4th week from week 4 to week 24 in patients with relapsing-remitting multiple sclerosis (RRMS). CUAL is defined as: new gadolinium [Gd]-enhanced lesions on T1-weighted, or new or enlarging lesions on T2-weighted MRI scans, without double counting.

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CLINICAL TRIAL NO: EU820UPV01 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF TRK-820 IN HEMODIALYSIS PATIENTS WITH UREMIC PRURITUS EudraCT No: 2005-003469-18 Short Title: TRK-820 UP 5µg To compare the efficacy of three times a week i.v. treatment with TRK-820 5µg versus placebo in hemodialysis patients with UP following completion of a four-week parallel-group treatment period. Previously conducted Phase III studies showed a trend towards statistically significant results on efficacy for i.v. 5µg TRK-820 three times a week over placebo in a parallel group study with four weeks treatment as well as in a cross-over study with treatment periods of two weeks each.

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Humoral and cellular immune response against tetanus and diphtheria following booster vaccination To analyze whether the immune response against tetanus and diphtheria is different in young adults vaccinated 10 years after the last vaccination compared to elderly individuals vaccinated 5 years after the last vaccination.

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AN OPEN-LABEL, NON-RANDOMIZED, MULTICENTER, TWO-STAGE, PHASE 2 STUDY OF S-1 IN CHEMOTHERAPY-NAIVE PATIENTS WITH LOCALLY ADVANCED OR METASTATIC PANCREATIC CANCER To evaluate the antitumor acitivity, as assessed by objective tumor response (overall response rate [ORR] of single agent S-1 in chemotherapy-naive patients with locally advanced or metastatic pancreatic cancer.

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Comparison of the effects of bupivacain or levobupivacain on cerebral oxigenation during intradural anesthesia in elderly patients who undergo hip replacement surgery Efecto sobre la oxigenación cerebral de la utilización de bupivacaína o levobupivacaína durante la anestesia intradural en el paciente anciano sometido a cirugía por fractura de fémur The main objective is to assess the effect of bupivacaine or levobupivacaine on peroperatory regional cerebral oximetry during anaesthesia in elderly patients undergoing hip replacement surgery El objetivo principal será evaluar el efecto sobre la oximetría regional cerebral peroperatoria (SrO2) de la utilización de bupivacaína o de levobupivacaína en la anestesia intradural en el paciente anciano sometido a cirugía ortopédica mayor por fractura de fémur

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An Eight- Week Randomized, Double-Blind, Placebo-Controlled, Parallel Group Proof of Concept Study to Assess the Efficacy, Safety and Tolerability as well as the Pharmacokinetic Profile of oral Solabegron (GW427353) 125mg and 50mg Administered Twice Daily vs Placebo in Women with Overactive Bladder The primary objective of this study is to compare the efficacy of solabegron 125mg and 50mg administered twice daily, to that of placebo in female subjects with OAB including symptoms of urgency with urge incontinence and frequency which may be associated with nocturia, but without bladder related pain.

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